Anti-TRIP4/ASC-1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-843A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-843A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Transcription coactivator which associates with nuclear receptors,... more

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Product information "Anti-TRIP4/ASC-1"

Protein function: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347). May play a role in the development of neuromuscular junction (PubMed:26924529). May play a role in late myogenic differentiation. [The UniProt Consortium]

Keywords:	Anti-ASC-1, Anti-TRIP-4, Anti-TR-interacting protein 4, Anti-Activating signal cointegrator 1, Anti-Thyroid receptor-interacting protein 4
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-843A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: human)
Immunogen:	synthetic peptide. The epitope recognized by A300-843A-T maps to a region between residue 225 and 275 of human Thyroid Hormone Receptor Interactor 4 (Activating Signal Cointegrator 1) using the numbering given in entry NP_057297.2 (GeneID 9325).
Format:	Antigen Affinity Purified