Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-857A-T 20 µl (2 blots) -

3 - 9 business days*

A301-857A-M 100 µl (10 blots) -

3 - 9 business days*

A301-857A 100 µl (20 µg) -

3 - 9 business days*

Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in... more
Product information "Anti-TRIM25"
Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784). [The UniProt Consortium]
Keywords: Anti-EFP, Anti-TRIM25, Anti-RING finger protein 147, Anti-Zinc finger protein 147, Anti-E3 ubiquitin/ISG15 ligase TRIM25, Anti-RING-type E3 ubiquitin transferase, Anti-Estrogen-responsive finger protein, Anti-Tripartite motif-containing protein 25
Supplier: Bethyl Laboratories
Supplier-Nr: A301-857A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A301-857A-T maps to a region between residue 325 and 375 of human tripartite motif-containing 25 using the numbering given in entry NP_005073.2 (GeneID 7706).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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