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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-856A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-856A | 100 µl | - |
2 - 8 business days* |
588.00€
|
Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in... more
Product information "Anti-TRIM25"
Protein function: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784). [The UniProt Consortium]
Keywords: | Anti-EFP, Anti-TRIM25, Anti-RING finger protein 147, Anti-Zinc finger protein 147, Anti-E3 ubiquitin/ISG15 ligase TRIM25, Anti-RING-type E3 ubiquitin transferase, Anti-Estrogen-responsive finger protein, Anti-Tripartite motif-containing protein 25 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-856A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic peptide. The epitope recognized by A301-856A-T maps to a region between residue 75 and 125 of human tripartite motif-containing 25 using the numbering given in entry NP_005073.2 (GeneID 7706). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K10652 | Matching products |
UniProt ID : | Q14258 | Matching products |
Gene ID | GeneID 7706 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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