Anti-TRAIL-R2 (human), clone TR2.21

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-20B-0028-C100	100 µg		-		3 - 9 business days*		396.00€

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Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Liquid. In PBS... more

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Product information "Anti-TRAIL-R2 (human), clone TR2.21"

Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Keywords:	TRAIL Receptor 2, DR5, KILLER, TNFRSF 10B, CD262
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-20B-0028

Properties

Application:	FC, IHC, WB
Antibody Type:	Monoclonal
Clone:	TR2.21
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human TRAIL-R2 (DR5).
Format:	Purified