Anti-TRAF6, ID (TRAF6, RNF85, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, I

Anti-TRAF6, ID (TRAF6, RNF85, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, I
Item number Size Datasheet Manual SDS Delivery time Quantity Price
043187-Biotin.200 200 µl - -

3 - 19 business days*

993.00€
 
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein... more
Product information "Anti-TRAF6, ID (TRAF6, RNF85, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, I"
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-TRAF6, Anti-RNF85, EC=6.3.2.-, Anti-RING finger protein 85, Anti-Interleukin-1 signal transducer, Anti-TNF receptor-associated factor 6, Anti-E3 ubiquitin-protein ligase TRAF6
Supplier: United States Biological
Supplier-Nr: 043187-Biotin

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: Biotin
Host: Rabbit
Species reactivity: human
Immunogen: TRAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human TRAF6.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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