Anti-TPP1

Anti-TPP1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-069A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-069A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-069A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Component of the shelterin complex (telosome) that is involved in the... more
Product information "Anti-TPP1"
Protein function: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis. [The UniProt Consortium]
Keywords: Anti-ACD, Anti-PIP1, Anti-POT1 and TIN2-interacting protein, Anti-Adrenocortical dysplasia protein homolog
Supplier: Bethyl Laboratories
Supplier-Nr: A303-069A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Rat)
Immunogen: synthetic peptide. The epitope recognized by A303-069A-T maps to a region between residue 150 and 200 of human Adrenocortical Dysplasia Homolog using the numbering given in entry NP_001075955.1 (GeneID 65057).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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