Anti-TPMT (Thiopurine S-methyltransferase, Thiopurine methyltransferase) (AP)

Anti-TPMT (Thiopurine S-methyltransferase, Thiopurine methyltransferase) (AP)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
134640-AP.100 100 µl - -

3 - 19 business days*

666.00€
 
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the... more
Product information "Anti-TPMT (Thiopurine S-methyltransferase, Thiopurine methyltransferase) (AP)"
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq], Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1ug/ml, 10ug/ml, Optimal dilutions to be determined by the researcher. AA Sequence: MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGKSGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKVFKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQYLLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRRLEKVDAFEERHKSWGIDCLFEKLYLLTEK, Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Supplier: United States Biological
Supplier-Nr: 134640-AP

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 1B5
Conjugate: No
Host: Mouse
Reactivity: Human
Format: Affinity Purified

Database Information

UniProt ID : P51580 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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