Anti-TL1A (TNFSF15, Tumor Necrosis Factor Ligand Superfamily Member 15)

Anti-TL1A (TNFSF15, Tumor Necrosis Factor Ligand Superfamily Member 15)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T8038-05B.100 100 µg - -

3 - 19 business days

549.00€
 
TL1A is also known as tumor necrosis factor ligand superfamily member 15 (TNFSF15). TL1A acts as... more
Product information "Anti-TL1A (TNFSF15, Tumor Necrosis Factor Ligand Superfamily Member 15)"
TL1A is also known as tumor necrosis factor ligand superfamily member 15 (TNFSF15). TL1A acts as a co-stimulator of IFN-gamma secretion through binding to DR3 (death domain receptor 3 or TRAMP) and may play an important role in Th1-mediated diseases such as Crohn's disease. In cells expressing DR3, TL1A induces NF-kappa-B activation and apoptosis. Decoy receptor 3 (DcR3) is also a receptor for TL1A. DcR3 can apparently neutralise the effect of TL1A, by inhibiting the TL1A-DR3 interaction, thereby inhibiting apoptosis. TL1A is specifically expressed on endothelial cells and is detected on monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon., , Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1.0ug/ml detects a band at ~27kD in PC-3 cell lysates, Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb , I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb I1904-46Q: IgG, H&L (HRP) Pab Gt xRb , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: T8038-05B

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A peptide corresponding to 14 amino acids near the amino terminus of human TL1A.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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