Anti-TIM-4 (T-cell Immunoglobulin and Mucin Domain-containing Protein 4, TIMD-4, Spleen, Mucin-conta

Anti-TIM-4 (T-cell Immunoglobulin and Mucin Domain-containing Protein 4, TIMD-4, Spleen, Mucin-conta
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T5469-94.100 100 µg - -

3 - 19 business days*

652.00€
 
TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing... more
Product information "Anti-TIM-4 (T-cell Immunoglobulin and Mucin Domain-containing Protein 4, TIMD-4, Spleen, Mucin-conta"
TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved. This monoclonal antibody blocks the engulfment of apoptotic cells by thymic macrophages. Applications: Suitable for use in Flow Cytometry, ELISA, Functional Studies and Immunofluorescence. Not suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-T-cell membrane protein 4, Anti-T-cell immunoglobulin and mucin domain-containing protein 4
Supplier: United States Biological
Supplier-Nr: T5469-94

Properties

Application: ELISA, FC, IF
Antibody Type: Monoclonal
Clone: Kat5-18
Conjugate: No
Host: Hamster
Species reactivity: mouse
Immunogen: Mouse peritoneal cells
Format: Affinity Purified

Database Information

UniProt ID : Q96H15 | Matching products
Gene ID GeneID 91937 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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