Anti-TFEB

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-673A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A303-673A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Transcription factor that specifically recognizes and binds E-box sequences... more
Product information "Anti-TFEB"
Protein function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. [The UniProt Consortium]
Keywords: Anti-TFEB, Anti-BHLHE35, Anti-bHLHe35, Anti-Transcription factor EB, Anti-Class E basic helix-loop-helix protein 35
Supplier: Bethyl Laboratories
Supplier-Nr: A303-673A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, bovine, dog, horse, guinea pig_10141, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, olive baboon, european domestic ferret, african elephant, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-673A-T maps to a region between residue 426 and 476 of human Transcription Factor EB using the numbering given in entry NP_009093.1 (GeneID 7942).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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