Anti-TFEB

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-673A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A303-673A-M 100 µl (10 blots) -

3 - 9 business days

290.00€
A303-673A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Transcription factor that specifically recognizes and binds E-box sequences... more
Product information "Anti-TFEB"
Protein function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. [The UniProt Consortium]
Keywords: Anti-TFEB, Anti-BHLHE35, Anti-bHLHe35, Anti-Transcription factor EB, Anti-Class E basic helix-loop-helix protein 35
Supplier-Nr: A303-673A-T

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Bovine, Dog, Horse, Guinea Pig_10141, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Olive Baboon, European Domestic Ferret, African Elephant, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-673A-T maps to a region between residue 426 and 476 of human Transcription Factor EB using the numbering given in entry NP_009093.1 (GeneID 7942).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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