Anti-TERT

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG54933.50 50 µl - -

6 - 14 business days*

436.00€
ARG54933.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of... more
Product information "Anti-TERT"
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA- dependent extension of 3'-chromosomal termini with the 6- nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis. [The UniProt Consortium]
Keywords: Anti-TP2, Anti-EST2, Anti-TERT, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated protein 2, Anti-Telomerase reverse transcriptase
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG54933

Properties

Application: ELISA, FC, ICC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: KLH-conjugated synthetic peptide around aa. 627-656 (Center) of Human TERT
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-TERT"
Write a review
or to review a product.
Viewed