Anti-TEM7 (Tumor Endothelial Marker 7, Plexin Domain Containing 1, Plexin Domain-containing Protein

Anti-TEM7 (Tumor Endothelial Marker 7, Plexin Domain Containing 1, Plexin Domain-containing Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T2500-01A.100 100 µg - -

3 - 19 business days*

479.00€
 
Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have... more
Product information "Anti-TEM7 (Tumor Endothelial Marker 7, Plexin Domain Containing 1, Plexin Domain-containing Protein"
Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9). TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain. TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis. The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis. Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: HCT-116 , Storage and Stability:, May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: T2500-01A

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: 9F189
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: This monoclonal antibody was developed by immunizing mice with a synthetic petide containing amino acids 411-427 of human TEM7.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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