Anti-TDP43, clone 3H8

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG10763.50 50 µl - -

6 - 14 business days*

439.00€
 
Protein function: DNA and RNA-binding protein which regulates transcription and splicing.... more
Product information "Anti-TDP43, clone 3H8"
Protein function: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR. [The UniProt Consortium]
Keywords: Anti-TDP43, Anti-TDP-43, Anti-TARDBP, Anti-TAR DNA-binding protein 43
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG10763

Properties

Application: WB, ICC, IF, IHC (frozen)
Antibody Type: Monoclonal
Clone: 3H8
Conjugate: No
Host: Mouse
Reactivity: Mouse, Rat
Immunogen: Full length recombinant Human TDP43 expressed in and purified from E. coli
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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