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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-AMAb91716.25 | 25 µl | - |
7 - 10 business days* |
240.00€
|
|||
ATA-AMAb91716.100 | 100 µl | - |
7 - 10 business days* |
358.00€
|
Protein function: Participates in the Wnt signaling pathway and modulates MYC expression by... more
Product information "Anti-TCF7L2, clone CL11547"
Protein function: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine. [The UniProt Consortium] Validated by standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Keywords: | Anti-TCF4, Anti-TCF-4, Anti-hTCF-4, Anti-TCF7L2, Anti-T-cell factor 4, Anti-Transcription factor 7-like 2, Anti-HMG box transcription factor 4, Anti-T-cell-specific transcription factor 4 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | AMAb91716 |
Properties
Application: | WB, IHC |
Antibody Type: | Monoclonal |
Clone: | CL11547 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Synthetic Peptide: IPDLTSPYLP NGSLSPTART |
Database Information
KEGG ID : | K04491 | Matching products |
UniProt ID : | Q9NQB0 | Matching products |
Gene ID | GeneID 6934 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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