Anti-TCF7L2, clone CL11547

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-AMAb91716.25 25 µl -

7 - 10 business days*

240.00€
ATA-AMAb91716.100 100 µl -

7 - 10 business days*

358.00€
 
Protein function: Participates in the Wnt signaling pathway and modulates MYC expression by... more
Product information "Anti-TCF7L2, clone CL11547"
Protein function: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine. [The UniProt Consortium] Validated by standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Keywords: Anti-TCF4, Anti-TCF-4, Anti-hTCF-4, Anti-TCF7L2, Anti-T-cell factor 4, Anti-Transcription factor 7-like 2, Anti-HMG box transcription factor 4, Anti-T-cell-specific transcription factor 4
Supplier: Atlas Antibodies
Supplier-Nr: AMAb91716

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: CL11547
Conjugate: No
Host: Mouse
Species reactivity: human, mouse
Immunogen: Synthetic Peptide: IPDLTSPYLP NGSLSPTART

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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