Anti-TBC1D23

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A305-870A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A305-870A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Putative Rab GTPase-activating protein which plays a role in vesicular... more
Product information "Anti-TBC1D23"
Protein function: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge. [The UniProt Consortium]
Keywords: Anti-TBC1D23, Anti-NS4ATP1, Anti-TBC1 domain family member 23, Anti-HCV non-structural protein 4A-transactivated protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A305-870A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, zebrafish, X. laevis, chicken, orangutan)
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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