Anti-TAG-72 Cocktail, clone B72.3 + CA72/733

Anti-TAG-72 Cocktail, clone B72.3 + CA72/733
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2364SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody recognizes an oncofetal... more
Product information "Anti-TAG-72 Cocktail, clone B72.3 + CA72/733"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma. Protein function: mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC. [The UniProt Consortium]
Keywords: Anti-tag-72, Anti-C25A1.3, EC=2.1.1.56, Anti-mRNA cap guanine-N7 methyltransferase, Anti-mRNA (guanine-N(7)-)-methyltransferase, TAG-72 Antibody Cocktail
Supplier: NSJ Bioreagents
Supplier-Nr: V2364SAF

Properties

Application: FC, IHC, IF
Antibody Type: Mixed
Clone: B72.3+CA72/733
Conjugate: No
Host: Mouse
Species reactivity: human, bovine, dog, rat
Immunogen: The membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3) and TAG-72 protein (CA72/733) were used as the immunogens for this antibody cocktail.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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