Anti-Synuclein alpha, CT

Anti-Synuclein alpha, CT
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S9500-21A.100 100 µg - -

1 - 19 business days

700.00€
 
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of... more
Product information "Anti-Synuclein alpha, CT"
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. An early step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43aa peptides (beta amyloid1-40, 1-42, and 1-43). Polymerization of b-amyloid (Ab) and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. Ab deposits have also been found to contain 2 additional proteins termed a-synuclein and b-synuclein. The 140aa a-synuclein is identical with non-Ab component (NACP) of AD. The 134aa b-synuclein is homologous to 14kD bovine phosphoneuroprotein 14. Mutations in a-synuclein gene causing a replacement of alanine with a threonine has the potential to cause the protein to misfold. Applications: Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application., Other applications not tested. Recommended Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well, Western Blot: 1-10ug/ml., Optimal dilutions to be determined by the researcher. Control Peptide: S9500-21P , Storage and Stability:, May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Alpha-synuclein, Anti-Non-A beta component of AD amyloid, Anti-Non-A4 component of amyloid precursor
Supplier: United States Biological
Supplier-Nr: S9500-21A

Properties

Application: ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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