Anti-Survivin (TIAP, API4)

Anti-Survivin (TIAP, API4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S8500-01B.50 50 µg - -

1 - 19 business days

650.00€
 
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is... more
Product information "Anti-Survivin (TIAP, API4)"
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): 2.5ug/ml, Western Blot: 0.5-1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-BIRC5, Anti-Apoptosis inhibitor 4, Anti-Apoptosis inhibitor survivin, Anti-Baculoviral IAP repeat-containing protein 5
Supplier: United States Biological
Supplier-Nr: S8500-01B

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide, KLH-conjugated. Epitope: peptide corresponding to amino acids near the carboxy-terminus of human survivin
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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