Anti-Structural Maintenance of Chromosomes 4 (SMC4, SMC-4, Chromosome-associated Polypeptide C, CAPC

The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1-3ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Ramos cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.