Anti-STAT2, clone 19G8.H2.H6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-301-B65S 25 µl - -

6 - 10 business days*

180.00€
200-301-B65 100 µg - -

6 - 10 business days*

698.00€
 
Protein function: Signal transducer and activator of transcription that mediates signaling by... more
Product information "Anti-STAT2, clone 19G8.H2.H6"
Protein function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [The UniProt Consortium]
Keywords: Anti-p113, Anti-STAT2, Anti-Signal transducer and activator of transcription 2
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-301-B65

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 19G8.H2.H6
Conjugate: No
Host: Mouse
Species reactivity: human (Expected: rat, mouse)
Immunogen: synthetic peptide corresponding to residues near the C-terminus of mouse STAT2
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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