Anti-SSX2IP

Anti-SSX2IP
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-298A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A303-298A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Belongs to an adhesion system, which plays a role in the organization of... more
Product information "Anti-SSX2IP"
Protein function: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling. Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). [The UniProt Consortium]
Keywords: Anti-ADIP, Anti-SSX2IP, Anti-KIAA0923, Anti-SSX2-interacting protein, Anti-Afadin DIL domain-interacting protein, Anti-Afadin- and alpha-actinin-binding protein
Supplier: Bethyl Laboratories
Supplier-Nr: A303-298A-T

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-298A-T maps to a region between residue 275 and 325 of human Synovial Sarcoma, X Breakpoint 2 Interacting Protein using the numbering given in entry NP_001159765.1 (GeneID 117178).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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