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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32163 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SNRPN (Small Nuclear Ribonucleoprotein... more
Product information "Anti-SNRPN"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N), also called SMN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame (SNURF) polypeptide. The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN also encodes a long alternatively spliced transcript containing several small nucleolar RNAs (snoRNAs) and extends downstream to partially overlap the UBE3A gene in the antisense orientation. PWS arises from loss of function of genes in this region expressed exclusively from the paternal chromosome, suggesting that SNRPN may play a role in its etiology. The SNRPN gene is mapped on 15q11.2. Analysis of maternal DNA and of SNRPN cDNA confirmed that the maternal allele is not expressed in fetal brain and heart. Deletions in the transcription unit of the imprinted SNRPN gene occur in patients who have PWS or Angelman syndrome because of a parental imprint switch failure in this chromosomal domain. Protein function: May be involved in tissue-specific alternative RNA processing events. [The UniProt Consortium]
Keywords: | Anti-SmN, Anti-Sm-N, Anti-Sm-D, Anti-SNRPN, Anti-HCERN3, Anti-snRNP-N, Anti-Sm protein N, Anti-Sm protein D, Anti-Tissue-specific-splicing protein, Anti-Small nuclear ribonucleoprotein-associated protein N, SNRPN Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32163 |
Properties
Application: | WB, IHC (paraffin), IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Amino acids QHIDYRMRCILQDGRIFIGTFKAFDKHMN of human SNRPN |
Format: | Purified |
Database Information
KEGG ID : | K11100 | Matching products |
UniProt ID : | P63162 | Matching products |
Gene ID | GeneID 6638 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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