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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
029611.100 | 100 µg | - | - |
3 - 19 business days* |
886.00€
|
Also known as Protein BRG1 and SNF2-beta, among other aliases, SMARCA4 a transcriptional... more
Product information "Anti-SMARCA4 (Transcription Activator BRG1, ATP-dependent Helicase SMARCA4, BRG1-associated Factor 1"
Also known as Protein BRG1 and SNF2-beta, among other aliases, SMARCA4 a transcriptional activator belonging to the SNF2/RAD54 helicase family, and acts as a component of the SWI/SNF ATP-dependent chromatin remodeling complexes family. BRG1 contains 4 domains of interest, a bromo domain, a helicase ATP-binding domain, a helicase C-terminal domain, and a HAS domain. It is a component of several different complexes with distinctive roles such as the CREST-BRG1 complex which regulates the activation of promoters in a calcium-dependent manner, releasing repressor complexes and recruiting activator complexes. It is also a part of the nBAF and npBAF complexes which are involved in the chromatin remodeling of mononucleosomes and nucleosomal arrays. As a component of the SWI/SNF complex, SMARCA4 has a role in tumor suppression and has been shown to regulate cell cycle and differentiation when present in neoplasma. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5ug/ml, Immunocytochemistry: 1ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: HeLa nuclear extract , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | 029611 |
Properties
Application: | ICC, WB |
Antibody Type: | Monoclonal |
Clone: | 13A219 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, rat |
Immunogen: | Recombinant responding to human SMARCA4 fused to GST-tag. |
Purity: | Purified by Protein G affinity chromatography. |
Database Information
KEGG ID : | K11647 | Matching products |
UniProt ID : | P51532 | Matching products |
Gene ID | GeneID 6597 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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