Anti-SMAD2, 3 (Mothers Against Decapentaplegic Homolog 2, MAD Homolog 2, Mothers Against DPP Homolog

Anti-SMAD2, 3 (Mothers Against Decapentaplegic Homolog 2, MAD Homolog 2, Mothers Against DPP Homolog
Item number Size Datasheet Manual SDS Delivery time Quantity Price
S1014-53A3.100 100 µl - -

4 - 22 business days

496.00€
 
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional... more
Product information "Anti-SMAD2, 3 (Mothers Against Decapentaplegic Homolog 2, MAD Homolog 2, Mothers Against DPP Homolog"
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Keywords: Anti-Smad2, Anti-hSMAD2, Anti-MAD homolog 2, Anti-SMAD family member 2, Anti-Mad-related protein 2, Anti-Mothers against DPP homolog 2, Anti-Mothers against decapentaplegic homolog 2
Supplier-Nr: S1014-53A3

Properties

Application: FC, IF, IP, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide corresponding to residues surrounding Ala208 of human Smad2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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