Anti-SKA3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-215A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-215A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer... more

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Product information "Anti-SKA3"

Protein function: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020). [The UniProt Consortium]

Keywords:	Anti-SKA3, Anti-C13orf3, Anti-Spindle and kinetochore-associated protein 3
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-215A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A304-215A-T maps to a region between residue 362 to 412 of human Spindle and Kinetochore Associated Complex Subunit 3 using the numbering given in entry NP_659498.4 (GeneID 221150).
Format:	Antigen Affinity Purified