Anti-SET2, NT (Histone-lysine N-methyltransferase SETD2, SET domain-containing protein 2, hSET2, Hun

Anti-SET2, NT (Histone-lysine N-methyltransferase SETD2, SET domain-containing protein 2, hSET2, Hun
Item number Size Datasheet Manual SDS Delivery time Quantity Price
041602.200 200 µl - -

1 - 19 business days

557.00€
 
SET2 is a histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36'... more
Product information "Anti-SET2, NT (Histone-lysine N-methyltransferase SETD2, SET domain-containing protein 2, hSET2, Hun"
SET2 is a histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This protein probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. SET2 binds DNA at promoters, and may act as a transcription activator. SET2 binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SET2 belongs to a class of huntingtin interacting proteins characterized by WW motifs. Applications: Suitable for use in Immunofluorescence, ICC, ELISA, Recommended Dilution: ELISA: 1:1,000, Immunohistochemistry: 1:50-100, Immunofluorescence, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-HIF1, Anti-HIF-1, Anti-HIP-1, Anti-hSET2, Anti-SETD2, Anti-p231HBP, EC=2.1.1.43, Anti-Huntingtin yeast partner B, Anti-Lysine N-methyltransferase 3A, Anti-SET domain-containing protein 2, Anti-Huntingtin-interacting protein 1
Supplier: United States Biological
Supplier-Nr: 041602

Properties

Application: ELISA, IF, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: SET2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21~50 amino acids from the N-terminal region of human SET2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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