Anti-SET1A

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB18231.50 50 µl - -

9 - 20 business days*

352.00€
G-CAB18231.100 100 µl -

9 - 20 business days*

448.00€
 
Protein function: Histone methyltransferase that catalyzes methyl group transfer from... more
Product information "Anti-SET1A"
Protein function: Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism (PubMed:25561738, PubMed:12670868). Part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:29937342, PubMed:31197650, PubMed:32346159). Responsible for H3K4me3 enriched promoters and transcriptional programming of inner mass stem cells and neuron progenitors during embryogenesis (PubMed:31197650). Required for H3K4me1 mark at stalled replication forks. Mediates FANCD2-dependent nucleosome remodeling and RAD51 nucleofilaments stabilization at reversed forks, protecting them from nucleolytic degradation (PubMed:29937342, PubMed:32346159). Does not methylate 'Lys-4' of histone H3 if the neighboring 'Lys-9' residue is already methylated (PubMed:12670868). [The UniProt Consortium]
Keywords: Anti-hSET1A, Anti-SETD1A, Anti-Lysine N-methyltransferase 2F, Anti-SET domain-containing protein 1A, Anti-Histone-lysine N-methyltransferase SETD1A, Anti-Set1/Ash2 histone methyltransferase complex subunit SET1, SET1A Rabbit pAb
Supplier: Assay Genie
Supplier-Nr: CAB18231

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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