Anti-SEMA4A, NT (SEMA4A, SEMAB, SEMB, Semaphorin-4A, Semaphorin-B)

Anti-SEMA4A, NT (SEMA4A, SEMAB, SEMB, Semaphorin-4A, Semaphorin-B)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
041542.200 200 µl - -

1 - 19 business days

557.00€
 
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins.... more
Product information "Anti-SEMA4A, NT (SEMA4A, SEMAB, SEMB, Semaphorin-4A, Semaphorin-B)"
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-SEMAB, Anti-SEMA4A, Anti-Sema B, Anti-Semaphorin-B, Anti-Semaphorin-4A
Supplier: United States Biological
Supplier-Nr: 041542

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human SEMA4A.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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