Anti-SCUBE2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57557.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Lipid-binding protein required for SHH long-range signaling by binding to the... more

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Product information "Anti-SCUBE2"

Protein function: Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid- modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687). [The UniProt Consortium]

Keywords:	Anti-CEGP1, Anti-Scube/You, Anti-Protein CEGP1, Anti-Signal peptide, CUB and EGF-like domain-containing protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57557

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 251-280 (Center) of Human SCUBE2
MW:	110 kD
Format:	Purified