Anti-SCAP1 / SKAP55

Anti-SCAP1 / SKAP55
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32275 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Src kinase-associated phosphoprotein 1 is... more
Product information "Anti-SCAP1 / SKAP55"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. Protein function: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. [The UniProt Consortium]
Keywords: Anti-pp55, Anti-SKAP1, Anti-SCAP1, Anti-SKAP-55, Anti-Src kinase-associated phosphoprotein 1, Anti-Src family-associated phosphoprotein 1, Anti-Src kinase-associated phosphoprotein of 55 kDa, SCAP1 Antibody / SKAP55
Supplier: NSJ Bioreagents
Supplier-Nr: R32275

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Immunogen: Amino acids RMAPHLRRDSKKESCFELTSQDRRSYE of human SKAP55 were used as the immunogen for the SKAP55 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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