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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32275 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Src kinase-associated phosphoprotein 1 is... more
Product information "Anti-SCAP1 / SKAP55"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. Protein function: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. [The UniProt Consortium]
Keywords: | Anti-pp55, Anti-SKAP1, Anti-SCAP1, Anti-SKAP-55, Anti-Src kinase-associated phosphoprotein 1, Anti-Src family-associated phosphoprotein 1, Anti-Src kinase-associated phosphoprotein of 55 kDa, SCAP1 Antibody / SKAP55 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32275 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat |
Immunogen: | Amino acids RMAPHLRRDSKKESCFELTSQDRRSYE of human SKAP55 were used as the immunogen for the SKAP55 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K17699 | Matching products |
UniProt ID : | Q86WV1 | Matching products |
Gene ID | GeneID 8631 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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