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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A303-690A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A303-690A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
Protein function: Host restriction nuclease involved in defense response to virus. Has dNTPase... more
Product information "Anti-SAMHD1"
Protein function: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827). [The UniProt Consortium]
Keywords: | Anti-MOP5, Anti-DCIP, Anti-MOP-5, Anti-SAMHD1, Anti-dNTPase, EC=3.1.5.-, Anti-Monocyte protein 5, Anti-Dendritic cell-derived IFNG-induced protein, Anti-SAM domain and HD domain-containing protein 1 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A303-690A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: gorilla, chimpanzee, primates, pygmy chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A303-690A-T maps to a region between residue 450 and 500 of human SAM Domain and HD Domain 1 using the numbering given in entry NP_056289.2 (GeneID 25939). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K22544 | Matching products |
UniProt ID : | Q9Y3Z3 | Matching products |
Gene ID | GeneID 25939 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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