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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S0050-85.100 | 100 µl | - | - |
3 - 19 business days* |
727.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase downstream of phosphoinositide-3... more
Product information "Anti-S6K1 Aly/REF-like Target alpha, beta (SKAR, 46 kDa DNA Polymerase delta Interaction Protein, p4"
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase downstream of phosphoinositide-3 kinase (PI3K) and the target of rapamycin, FRAP/mTOR. p70 S6 kinase is required for cell growth and cell cycle progression (1,2). SKAR is a recently discovered substrate of S6K1. SKAR exists in two isoforms, a and b, the latter having a 29aa truncation. Phosphorylation of SKAR is mitogen-induced and sensitive to rapamycin. Reduction in SKAR protein levels results in decreased cell size, further implicating SKAR in cell growth control (3). Applications: Suitable for use in Immunofluorescence/Immunocytochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Immunofluorescence (IF-IC): 1:3200, Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-S6K1 Aly/REF-like target, Anti-Polymerase delta-interacting protein 3, Anti-46 kDa DNA polymerase delta interaction protein |
Supplier: | United States Biological |
Supplier-Nr: | S0050-85 |
Properties
Application: | ICC, IF, WB |
Antibody Type: | Monoclonal |
Clone: | 11C1067(D65E8) |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, monkey, mouse, rat |
Immunogen: | Synthetic peptide corresponding to the amino terminus of human SKAR. |
Format: | Purified |
Database Information
KEGG ID : | K22414 | Matching products |
UniProt ID : | Q9BY77 | Matching products |
Gene ID | GeneID 84271 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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