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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay20208-1 | 1 each | - |
6 - 10 business days* |
422.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G protein-coupled... more
Product information "Anti-S1P1 (protein A-purified)"
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 primarily couples with pertussis toxin-sensitive Gi/o proteins to mediate S1P-induced cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Expression of S1P1 is abundant in embryological vasculature and is ubiquitously expressed in adult cells, suggesting diverse physiological functions of this receptor. The human and mouse S1P1 receptors have 382 amino acids with an estimated molecular weight of 43 kDa. Glycosylation at the N-terminal extracellular domain may cause the protein to migrate at a higher position in SDS-PAGE. Cayman's S1P1 Polyclonal Antibody (protein A-purified) can be used for western blot applications. The antibody recognizes S1P1 at 42 kDa from human, mouse, porcine, and rat samples.Synonyms: EDG-1, S1PR1, Sphingosine-1-phosphate Receptor 1. Immunogen: Peptide from the internal region of human S1P1. Formulation: (Request formulation change), 500 µl of protein-A purified polyclonal antibody. Storage Buffer: TBS, pH 7.4, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide. Host: Rabbit. Applications: WB. UniProt Accession #: P21453.
Keywords: | Anti-S1P1, Anti-S1P1, Anti-S1PR1, Anti-CD363, Anti-CD363, Anti-CHEDG1, Anti-S1P receptor 1, Anti-S1P receptor 1, Anti-S1P receptor Edg-1, Anti-S1P receptor Edg-1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphin |
Supplier: | Cayman Chemical |
Supplier-Nr: | 20208 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, swine, rat |
Immunogen: | Peptide from the internal region of human S1P1 |
MW: | 42 kD |
Format: | Purified |
Database Information
KEGG ID : | K04288 | Matching products |
UniProt ID : | P21453 | Matching products |
Gene ID | GeneID 1901 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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