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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-569A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-569A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
Protein function: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K... more
Product information "Anti-Rubicon"
Protein function: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745). [The UniProt Consortium]
Keywords: | Anti-Baron, Anti-Rubicon, Anti-KIAA0226, Anti-Beclin-1 associated RUN domain containing protein, Anti-Run domain Beclin-1-interacting and cysteine-rich domain-containing protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-569A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: rhesus monkey, gorilla, chimpanzee, crab-eating macaque) |
Immunogen: | synthetic peptide. The epitope recognized by A302-569A-T maps to a region between residue 922 and 972 of human Rubicon using the numbering given in entry NP_055502.1 (GeneID 9711). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K19330 | Matching products |
UniProt ID : | Q92622 | Matching products |
Gene ID | GeneID 9711 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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