Anti-RPGR

Anti-RPGR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4374 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. X-linked retinitis pigmentosa GTPase... more
Product information "Anti-RPGR"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. Protein function: Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. May be involved in microtubule organization and regulation of transport in primary cilia. [The UniProt Consortium]
Keywords: Anti-RP3, Anti-RPGR, Anti-X-linked retinitis pigmentosa GTPase regulator, RPGR Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4374

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: rat
Immunogen: A recombinant human protein corresponding to amino acids A13-F338 was used as the immunogen for the RPGR antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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