Anti-RPGR

Anti-RPGR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-60472.60 60 µl -

7 - 16 business days*

198.00€
E-AB-60472.120 120 µl -

7 - 16 business days*

317.00€
E-AB-60472.200 200 µl -

7 - 16 business days*

525.00€
 
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the... more
Product information "Anti-RPGR"
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. Protein function: Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. May be involved in microtubule organization and regulation of transport in primary cilia. [The UniProt Consortium]
Keywords: Anti-RP3, Anti-RPGR, Anti-X-linked retinitis pigmentosa GTPase regulator, RPGR Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-60472

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant protein of human RPGR

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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