Anti-RNASEN / Drosha, Internal

Anti-RNASEN / Drosha, Internal
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG64087.100 100 µg - -

6 - 14 business days*

784.00€
 
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is... more
Product information "Anti-RNASEN / Drosha, Internal"
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. [The UniProt Consortium]
Keywords: Anti-RN3, Anti-p241, Anti-DROSHA, Anti-RNase III, EC=3.1.26.3, Anti-Protein Drosha, Anti-Ribonuclease 3, Anti-Ribonuclease III
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG64087

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human (Expected: mouse, rat, canine)
Immunogen: C-KQTDKQKLAQRE
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-RNASEN / Drosha, Internal"
Write a review
or to review a product.
Viewed