Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5) (AP)

Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5) (AP)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040988-AP.200 200 µl - -

3 - 19 business days*

790.00€
 
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II... more
Product information "Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5) (AP)"
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Supplier: United States Biological
Supplier-Nr: 040988-AP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Format: Affinity Purified

Database Information

UniProt ID : P48382 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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