Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5)

Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040988.200 200 µl - -

3 - 19 business days*

582.00€
 
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II... more
Product information "Anti-RFX5, ID (RFX5, DNA-binding protein RFX5, Regulatory factor X 5)"
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-RFX5, Anti-Regulatory factor X 5, Anti-DNA-binding protein RFX5
Supplier: United States Biological
Supplier-Nr: 040988

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: RFX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-266 amino acids from the Central region of human RFX5.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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