Anti-RBM5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-15336.20 20 µl -

7 - 16 business days*

71.00€
E-AB-15336.60 60 µl -

7 - 16 business days*

143.00€
E-AB-15336.120 120 µl -

7 - 16 business days*

238.00€
E-AB-15336.200 200 µl -

7 - 16 business days*

396.00€
 
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that... more
Product information "Anti-RBM5"
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. Protein function: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. [The UniProt Consortium]
Keywords: Anti-H37, Anti-RBM5, Anti-Protein G15, Anti-RNA-binding protein 5, Anti-RNA-binding motif protein 5, Anti-Putative tumor suppressor LUCA15, Anti-Renal carcinoma antigen NY-REN-9, RBM5 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-15336

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human RBM5
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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