Anti-RBL2, NT (RBL2, RB2, Retinoblastoma-like protein 2, 130kD retinoblastoma-associated protein, Re

Anti-RBL2, NT (RBL2, RB2, Retinoblastoma-like protein 2, 130kD retinoblastoma-associated protein, Re
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040879.200 200 µl - -

1 - 19 business days

557.00€
 
RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin... more
Product information "Anti-RBL2, NT (RBL2, RB2, Retinoblastoma-like protein 2, 130kD retinoblastoma-associated protein, Re"
RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. RBL2 may act as a tumor suppressor. Applications: Suitable for use in Western Blot, Flow Cytometry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Flow Cytometry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-RB2, Anti-RBL2, Anti-pRb2, Anti-p130, Anti-RBR-2, Anti-Retinoblastoma-like protein 2, Anti-Retinoblastoma-related protein 2, Anti-130 kDa retinoblastoma-associated protein
Supplier: United States Biological
Supplier-Nr: 040879

Properties

Application: ELISA, FC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: RBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the N-terminal region of human RBL2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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