Anti-RBL1, CT (RBL1, Retinoblastoma-like protein 1, 107kD retinoblastoma-associated protein, pRb1)

Anti-RBL1, CT (RBL1, Retinoblastoma-like protein 1, 107kD retinoblastoma-associated protein, pRb1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040878.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is similar in sequence and possibly function to the product of... more
Product information "Anti-RBL1, CT (RBL1, Retinoblastoma-like protein 1, 107kD retinoblastoma-associated protein, pRb1)"
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-RBL1, Anti-pRb1, Anti-p107, Anti-Retinoblastoma-like protein 1, Anti-107 kDa retinoblastoma-associated protein
Supplier: United States Biological
Supplier-Nr: 040878

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: RBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1006-1035 amino acids from the C-terminal region of human RBL1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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