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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-DW9 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
Anti-RBBP8 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-RBBP8"
Anti-RBBP8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with RBBP8 from other sources has not been determined. Protein function: Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations. [The UniProt Consortium]
Keywords: | Anti-RIM, Anti-CtIP, Anti-CTIP, Anti-SAE2, Anti-RBBP8, Anti-RBBP-8, EC=3.1.-.-, Anti-DNA endonuclease RBBP8, Anti-CtBP-interacting protein, Anti-Retinoblastoma-binding protein 8, Anti-Retinoblastoma-interacting protein and myosin-like, Anti-Sporulation in |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-DW9 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 14 amino acid synthetic peptide near the internal region of human RBBP8. |
Format: | Purified |
Database Information
KEGG ID : | K20773 | Matching products |
UniProt ID : | Q99708 | Matching products |
Gene ID | GeneID 5932 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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