Anti-RBBP7 (Nucleosome-remodeling Factor Subunit RBAP46, Histone Acetyltransferase Type B Subunit 2,

Anti-RBBP7 (Nucleosome-remodeling Factor Subunit RBAP46, Histone Acetyltransferase Type B Subunit 2,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1665-35D.20 20 µl - -

1 - 19 business days

330.00€
R1665-35D.100 100 µl - -

1 - 19 business days

566.00€
 
Retinoblastoma-associated proteins 46 and 48 (RBAP46 and RBAP48, also known as RBBP7 and RBBP4)... more
Product information "Anti-RBBP7 (Nucleosome-remodeling Factor Subunit RBAP46, Histone Acetyltransferase Type B Subunit 2,"
Retinoblastoma-associated proteins 46 and 48 (RBAP46 and RBAP48, also known as RBBP7 and RBBP4) were first characterized in human cells as proteins that bind to the retinoblastoma (Rb) tumor suppressor protein (1). Since then, these proteins have been shown to be components of many protein complexes involved in chromatin regulation, including the chromatin assembly factor 1 (CAF-1) complex and type B histone acetyltransferase complex HAT1, both of which function in chromatin assembly during DNA replication (2,3). RBAP46 and RBAP48 are also found in the nucleosome remodeling factor complex NURF, the nucleosome remodeling and histone de-acetylation complex NuRD, and the Sin3/HDAC histone de-acetylation complex (4-7). More recently, RBAB46 and RBAP48 were identified as components of the polycomb repressor complex PRC2, which also contains EED and Ezh2 (8). RBAP46 and RBAP48 bind to the histone fold region of histone H4 and are believed to target these chromatin remodeling, histone acetylation, and histone de-acetylation complexes to their histone substrates (3). Applications: Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Immunofluorescence (IF-IC): 1:600, Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Immunoprecipitation: 1:50 , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Histone-binding protein RBBP7, Anti-Retinoblastoma-binding protein 7, Anti-Retinoblastoma-binding protein p46, Anti-Histone acetyltransferase type B subunit 2, Anti-Nucleosome-remodeling factor subunit RBAP46
Supplier: United States Biological
Supplier-Nr: R1665-35D

Properties

Application: IF, IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide corresponding to residues near the C-terminus of human RBAP46.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: °C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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