Anti-RbBP5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-109A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-109A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: In embryonic stem (ES) cells, plays a crucial role in the differentiation... more
Product information "Anti-RbBP5"
Protein function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters (PubMed:19131338). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3 (PubMed:19556245). Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:19556245). In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (PubMed:22266653, PubMed:21220120). [The UniProt Consortium]
Keywords: Anti-RBQ3, Anti-RBBP5, Anti-RBBP-5, Anti-Retinoblastoma-binding protein 5, Anti-Retinoblastoma-binding protein RBQ-3
Supplier: Bethyl Laboratories
Supplier-Nr: A300-109A

Properties

Application: WB, IP, IHC, ChIP, ChIP-chip, ChIP-Seq
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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