Anti-RanBP3 (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00295-T 10 µl (5+ slides) -

3 - 9 business days

IHC-00295 100 µl (50+ slides) -

3 - 9 business days

Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export... more
Product information "Anti-RanBP3 (IHC)"
Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF- beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. [The UniProt Consortium]
Keywords: Anti-RanBP3, Anti-RANBP3, Anti-Ran-binding protein 3
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00295


Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: X. Laevis, X. Tropicalis, Chicken, Bovine, Dog, Horse, Rabbit, Guinea Pig_10141, Panda, Orangutan, Monkey, Gorilla)
Immunogen: synthetic peptide. The epitope recognized by IHC-00295 maps to a region between residue 150 and 200 of human RAN binding protein 3 using the numbering given in entry NP_015561.1 (GeneID 8498).
Format: Antigen Affinity Purified

Handling & Safety

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Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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