Anti-RanBP3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-520A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-520A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-520A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export... more
Product information "Anti-RanBP3"
Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF- beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. [The UniProt Consortium]
Keywords: Anti-RanBP3, Anti-RANBP3, Anti-Ran-binding protein 3
Supplier: Bethyl Laboratories
Supplier-Nr: A301-520A

Properties

Application: WB, IP, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A301-520A-T maps to a region between residue 150 and 200 of human RAN binding protein 3 using the numbering given in entry NP_015561.1 (GeneID 8498).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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