Anti-RanBP2

Anti-RanBP2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-797A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A301-797A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I.... more
Product information "Anti-RanBP2"
Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle (PubMed:20386726). [The UniProt Consortium]
Keywords: Anti-p270, Anti-RanBP2, Anti-RANBP2, Anti-NUP358, EC=6.3.2.-, Anti-Nucleoporin Nup358, Anti-358 kDa nucleoporin, Anti-Ran-binding protein 2, Anti-E3 SUMO-protein ligase RanBP2, Anti-Nuclear pore complex protein Nup358
Supplier: Bethyl Laboratories
Supplier-Nr: A301-797A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A301-797A-T maps to a region between residue 2600 and 2650 of human RAN binding protein 2 using the numbering given in entry NP_006258.3 (GeneID 5903).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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