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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-797A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-797A | 100 µl | - |
2 - 8 business days* |
588.00€
|
Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I.... more
Product information "Anti-RanBP2"
Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle (PubMed:20386726). [The UniProt Consortium]
Keywords: | Anti-p270, Anti-RanBP2, Anti-RANBP2, Anti-NUP358, EC=6.3.2.-, Anti-Nucleoporin Nup358, Anti-358 kDa nucleoporin, Anti-Ran-binding protein 2, Anti-E3 SUMO-protein ligase RanBP2, Anti-Nuclear pore complex protein Nup358 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-797A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A301-797A-T maps to a region between residue 2600 and 2650 of human RAN binding protein 2 using the numbering given in entry NP_006258.3 (GeneID 5903). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12172 | Matching products |
UniProt ID : | P49792 | Matching products |
Gene ID | GeneID 5903 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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