Anti-RAB5A

Anti-RAB5A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-40241.20 20 µl - -

7 - 16 business days*

55.00€
E-AB-40241.60 60 µl - -

7 - 16 business days*

109.00€
E-AB-40241.120 120 µl - -

7 - 16 business days*

200.00€
E-AB-40241.200 200 µl - -

7 - 16 business days*

328.00€
 
Rab5a belongs to the Rab GTPases family proteins,which play roles in endocytosis,exocytosis,and... more
Product information "Anti-RAB5A"
Rab5a belongs to the Rab GTPases family proteins,which play roles in endocytosis,exocytosis,and vesicular transportation. Rab family proteins were recently reported to play important roles in human cancer progression. Rab5a was reported to be overexpressed in breast and ovarian cancers and associated with proliferation and invasion. Protein function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell- containing phagosomes, probably downstream of DYN2 and PIK3C3. [The UniProt Consortium]
Keywords: Anti-RAB5, Anti-RAB5A, Anti-Ras-related protein Rab-5A, RAB5A Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-40241

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human Ras-related protein Rab-5A protien

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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