Anti-PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoant

Anti-PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoant
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040674.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.... more
Product information "Anti-PTPRN2, NT (PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoant"
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-IAR, Anti-ICAAR, Anti-PTPRN2, Anti-Phogrin, Anti-KIAA0387, Anti-R-PTP-N2, EC=3.1.3.48, Anti-Islet cell autoantigen-related protein, Anti-Receptor-type tyrosine-protein phosphatase N2
Supplier: United States Biological
Supplier-Nr: 040674

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the N-terminal region of human PTPRN2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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